Bioactive functional materials: a perspective on phosphate-based glasses

Abou Neel, Ensanya A, Pickup, David M, Valappil, Sabeel P ORCID: 0000-0001-9646-8406, Newport, Robert J and Knowles, Jonathan C (2009) Bioactive functional materials: a perspective on phosphate-based glasses. JOURNAL OF MATERIALS CHEMISTRY, 19 (6). pp. 690-701.

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Official URL: http://dx.doi.org/10.1039/b810675d

Abstract

The general trend in biomaterials is to use and employ materials that play an active role in tissue regeneration rather than passive and inert materials. Therefore, understanding how a material interacts with the surrounding environments, including cells and tissue fluid, allows material design to be tailored so that implants can be constructed to promote a specific biological response, helping them better perform their function. This class of materials has been described as the "Third Generation" of biomaterials. Phosphate based glasses fall into this category and it has been shown that the properties of these glasses can be tuned via their composition according to the desired end application. These glasses can be prepared as melt-quenched or sol-gel bulk form suitable for potential hard tissue engineering applications and as vehicles for antimicrobial agents. They can also be prepared as fibres suitable for soft tissue engineering applications such as those involving muscle, ligaments, and tendon, where, like the fibres, the tissue has a high degree of anisotropy. © 2009 The Royal Society of Chemistry.

Item Type:	Article
Additional Information:	MATCHED FROM WOS ## TULIP Type: Articles/Papers (Journal) ## official_url: www.rsc.org/Publishing/Journals/JM/Article.asp?Type=AdvArticle
Uncontrolled Keywords:	IN-VITRO BIOACTIVITY, SINUS FLOOR ELEVATION, POROUS-SURFACED IMPLANTS, CONTROLLED-RELEASE GLASS, ENHANCED OSTEOCONDUCTIVITY, STREPTOCOCCUS-SANGUIS, METAPHOSPHATE GLASSES
Subjects:	?? RK ??
Divisions:	Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences > School of Dentistry
Depositing User:	Symplectic Admin
Date Deposited:	02 Jul 2009 11:39
Last Modified:	19 Jan 2023 07:38
DOI:	10.1039/b810675d
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/1163