Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom

Jameson, Lisa J, Newton, Autilia, Coole, Louise, Newman, Edmund NC, Carroll, Miles W, Beeching, Nick J ORCID: 0000-0002-7019-8791, Hewson, Roger and Christley, Robert M (2014) Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom. VIRUSES-BASEL, 6 (2). pp. 524-534.

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Official URL: http://dx.doi.org/10.3390/v6020524

Abstract

Hantaviruses are an established cause of haemorrhagic fever with renal syndrome (HFRS) in Europe. Following a confirmed case of HFRS in the UK, in an individual residing on a farm in North Yorkshire and the Humber, a tidal estuary on the east coast of Northern England, and the subsequent isolation of a Seoul hantavirus from rats trapped on the patient's farm, it was considered appropriate to further investigate the public health risk of this virus in the region. Of a total 119 individuals tested, nine (7.6%) were seropositive for hantavirus antibodies. Seven of the seropositive samples showed a stronger reaction to Seoul and Hantaan compared to other clinically relevant hantaviruses. Observation of rodents during the day, in particular mice, was associated with a reduced risk of seropositivity. In addition to one region known to be at risk following an acute case, five further potential risk areas have been identified. This study supports recently published evidence that hantaviruses are likely to be of public health interest in the region.

Item Type:	Article
Additional Information:	Published 5 February 2014
Uncontrolled Keywords:	farmers, hantavirus, serology, saliva, serosurveillance, haemorrhagic fever with renal syndrome, Seoul virus
Subjects:	?? RA0421 ??
Depositing User:	Symplectic Admin
Date Deposited:	20 Nov 2014 16:42
Last Modified:	15 Dec 2022 16:25
DOI:	10.3390/v6020524
Publisher's Statement :	© 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/2002323