Use of immunohistochemical staining and electron microscopy to aid in diagnosis of soft tissue sarcomas associated with the fetlock joint in two horses

Findley, JA, Singer, ER, Milner, PI and Leeming, G ORCID: 0000-0003-3409-399X (2014) Use of immunohistochemical staining and electron microscopy to aid in diagnosis of soft tissue sarcomas associated with the fetlock joint in two horses. Journal of Veterinary Diagnostic Investigation, 26 (3). pp. 465-469.

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Abstract

Soft tissue sarcomas of the equine distal limb associated with joints, sheaths, or bursae have rarely been reported. Accurate diagnosis of these tumors is challenging in both human beings and veterinary species. Immunohistochemical staining and transmission electron microscopy have been used in human beings to reduce misdiagnosis. The current report describes 2 mature horses presenting with lameness and swelling associated with the dorsal aspect of the metacarpo(tarso)phalangeal joint. In both cases, surgical excision was performed with subsequent histological analysis of the masses to determine the tissue of origin. In both cases, immunohistochemical staining and transmission electron microscopy aided the definitive diagnosis of fibrosarcoma associated with the fetlock joints of 2 horses.

Item Type:	Article
Uncontrolled Keywords:	Electron microscopy, equine, immunohistochemical staining, soft tissue sarcoma
Depositing User:	Symplectic Admin
Date Deposited:	23 Mar 2015 12:08
Last Modified:	15 Dec 2022 08:03
DOI:	10.1177/1040638714529951
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/2007320