Investigation of the temporal properties of the retina using the m-sequence.

Hagan, Richard P, Fisher, Anthony C and Brown, Malcolm C (2011) Investigation of the temporal properties of the retina using the m-sequence. Documenta ophthalmologica. Advances in ophthalmology, 123 (3). 179 - 185.

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Abstract

The mfERG provides a topographic map of function of the retina and has been used in numerous studies to identify macular, paramacular and peripheral retinal dysfunction. This study investigates the changes in response due to the presentation rate of the stimulus. Twenty subjects gave informed consent to take part in the study, which had local regional ethical committee approval. Only a single hexagon of 8° diameter was presented to reduce ambiguity when identifying the higher-order kernels (HOK). Six rates were tested using a 60-Hz CRT monitor by introducing blank (black ~0 cd/m2) filler frames (FF). The rates tested were 0FF; 1FF; 2FF; 4FF; 7FF; and 14FF. The first-order kernel had largest responses to the slower stimuli (4FF and above). HOK had largest amplitudes at faster rates with the second-order kernel peaking at 1FF. At rates with 4FF and slower, the higher-order kernels were indiscernible above the noise.

Item Type:	Article
Uncontrolled Keywords:	Retina, Humans, Electroretinography, Photic Stimulation, Reference Values, Adult, Male, Young Adult
Subjects:	?? QA ?? ?? RE ??
Depositing User:	Symplectic Admin
Date Deposited:	28 Oct 2015 16:51
Last Modified:	07 Jun 2022 07:10
DOI:	10.1007/s10633-011-9295-9
URI:	https://livrepository.liverpool.ac.uk/id/eprint/2034223