Sono-Assembly of Highly Biocompatible Polysaccharide Capsules for Hydrophobic Drug Delivery



Wang, Hongqiang, Yan, Xuehai, Li, Guo Liang, Pilz-Allen, Christine, Moehwald, Helmuth and Shchukin, Dmitry ORCID: 0000-0002-2936-804X
(2014) Sono-Assembly of Highly Biocompatible Polysaccharide Capsules for Hydrophobic Drug Delivery. ADVANCED HEALTHCARE MATERIALS, 3 (6). pp. 825-831.

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Abstract

Cells like sugar. General synthesis and potential of intracellular hydrophobic drug delivery of single-component polysaccharide capsules are pursued. The capsules can be generally assembled through hydrogen bonding networks but show striking shell robustness. The evidenced cell internalization, stimuli-responsiveness to local pH changes and high biocompatibilities of the capsules specifically favor their potential intracellular drug delivery.

Item Type: Article
Additional Information: ## TULIP Type: Articles/Papers (Journal) ##
Uncontrolled Keywords: NIH 3T3 Cells, Animals, Mice, Toluene, Fluorescein-5-isothiocyanate, Chitosan, Polysaccharides, Biocompatible Materials, Pharmaceutical Preparations, Capsules, Drug Carriers, Microscopy, Confocal, Temperature, Hydrogen-Ion Concentration, Sonication, Hydrophobic and Hydrophilic Interactions
Subjects: ?? QD ??
Depositing User: Symplectic Admin
Date Deposited: 12 Jan 2016 11:27
Last Modified: 15 Dec 2022 16:30
DOI: 10.1002/adhm.201300596
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/2046240

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