Understanding the physiological roles of the neuronal calcium sensor proteins



Burgoyne, Robert D ORCID: 0000-0002-9219-0387 and Haynes, Lee P ORCID: 0000-0002-1296-0338
(2012) Understanding the physiological roles of the neuronal calcium sensor proteins. MOLECULAR BRAIN, 5 (1). 2-.

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Abstract

Calcium signalling plays a crucial role in the control of neuronal function and plasticity. Changes in neuronal Ca2+ concentration are detected by Ca2+-binding proteins that can interact with and regulate target proteins to modify their function. Members of the neuronal calcium sensor (NCS) protein family have multiple non-redundant roles in the nervous system. Here we review recent advances in the understanding of the physiological roles of the NCS proteins and the molecular basis for their specificity.

Item Type: Article
Additional Information: Journal article Molecular brain Mol Brain. 2012 Jan 23;5(1):2. ## TULIP Type: Articles/Papers (Journal) ##
Uncontrolled Keywords: Calcium, Calcium-sensor, EF-hand, neuronal signalling, protein complex, protein structure
Depositing User: Symplectic Admin
Date Deposited: 28 Apr 2016 10:18
Last Modified: 19 Jan 2023 07:37
DOI: 10.1186/1756-6606-5-2
Open Access URL: http://molecularbrain.biomedcentral.com/articles/1...
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3000899