Skyler, Jay S, Bakris, George L, Bonifacio, Ezio, Darsow, Tamara, Eckel, Robert H, Groop, Leif, Groop, Per-Henrik, Handelsman, Yehuda, Insel, Richard A, Mathieu, Chantal et al (show 7 more authors)
(2017)
Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis.
DIABETES, 66 (2).
pp. 241-255.
Text
DB16-0806R2_110816_CLEAN COPY.docx - Author Accepted Manuscript Download (297kB) |
Abstract
The American Diabetes Association, JDRF, the European Association for the Study of Diabetes, and the American Association of Clinical Endocrinologists convened a research symposium, "The Differentiation of Diabetes by Pathophysiology, Natural History and Prognosis" on 10-12 October 2015. International experts in genetics, immunology, metabolism, endocrinology, and systems biology discussed genetic and environmental determinants of type 1 and type 2 diabetes risk and progression, as well as complications. The participants debated how to determine appropriate therapeutic approaches based on disease pathophysiology and stage and defined remaining research gaps hindering a personalized medical approach for diabetes to drive the field to address these gaps. The authors recommend a structure for data stratification to define the phenotypes and genotypes of subtypes of diabetes that will facilitate individualized treatment.
Item Type: | Article |
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Uncontrolled Keywords: | Humans, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetes Complications, Disease Progression, Hypoglycemic Agents, Prognosis, Risk Factors, Genotype, Phenotype, Precision Medicine |
Depositing User: | Symplectic Admin |
Date Deposited: | 04 Jan 2017 08:55 |
Last Modified: | 19 Jan 2023 07:23 |
DOI: | 10.2337/db16-0806 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3005060 |