Angiomatoid fibrous histiocytoma: A case of local recurrence and metastases to loco-regional lymph nodes that responded to chemotherapy



Ogden, S, Harave, S, McPartland, J, Brennan, B, Jeys, L, Losty, P ORCID: 0000-0003-0841-5879 and Pizer, B
(2016) Angiomatoid fibrous histiocytoma: A case of local recurrence and metastases to loco-regional lymph nodes that responded to chemotherapy. Pediatric Blood & Cancer, 64 (6). e26376-e26376.

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Abstract

Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumour with intermediate malignant potential. We report the case of a patient with local recurrence of AFH in two locations and lymph node metastases 18 months after primary surgical excision. The patient was treated with six cycles of ifosfamide and doxorubicin chemotherapy and a further three courses of ifosfamide monotherapy. Reassessment imaging showed a good response to chemotherapy with reduction in size of the two tumours of local recurrence and the lymph node metastases. This case demonstrates that AFH can respond to chemotherapy, even though it is rarely used.

Item Type: Article
Uncontrolled Keywords: angiomatoid, chemotherapy, fibrous, histiocytoma, treatment
Depositing User: Symplectic Admin
Date Deposited: 18 Apr 2017 08:31
Last Modified: 02 Oct 2023 17:59
DOI: 10.1002/pbc.26376
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3006982