Integration of cellular ubiquitin and membrane traffic systems: focus on deubiquitylases

Clague, Michael J ORCID: 0000-0003-3355-9479 and Urbe, Sylvie ORCID: 0000-0003-4735-9814 (2017) Integration of cellular ubiquitin and membrane traffic systems: focus on deubiquitylases. FEBS JOURNAL, 284 (12). pp. 1753-1766.

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Abstract

The cell is comprised of integrated multilevel protein networks or systems. The ubiquitin, protein homeostasis and membrane trafficking systems are highly integrated. Here, we look at the influence of reversible ubiquitylation on membrane trafficking and organelle dynamics. We review the regulation of endocytic sorting, selective autophagy and the secretory pathway by ubiquitin signals, with a particular focus on detailing the contribution of deubiquitylating enzymes.

Item Type:	Article
Uncontrolled Keywords:	autophagy, deubiquitylase, endocytosis, mitophagy, ubiquitin
Depositing User:	Symplectic Admin
Date Deposited:	18 May 2017 06:21
Last Modified:	19 Jan 2023 07:04
DOI:	10.1111/febs.14007
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3007511