Oral Ulcers in Juvenile-Onset Systemic Lupus Erythematosus: A Review of the Literature

Rodsaward, Pongsawat, Prueksrisakul, Titipong, Deekajorndech, Tawatchai, Edwards, Steven W ORCID: 0000-0002-7074-0552, Beresford, Michael W ORCID: 0000-0002-5400-9911 and Chiewchengchol, Direkrit ORCID: 0000-0003-1824-7012 (2017) Oral Ulcers in Juvenile-Onset Systemic Lupus Erythematosus: A Review of the Literature. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 18 (6). pp. 755-762.

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Abstract

Oral ulcers are the most common mucosal sign in juvenile-onset systemic lupus erythematosus (JSLE). The ulcers are one of the key clinical features; however, the terminology of oral ulcers, especially in JSLE patients, is often vague and ill-defined. In fact, there are several clinical manifestations of oral ulcers in JSLE, and some lesions occur when the disease is active, indicating that early management of the disease should be started. Oral ulcers are classified as lupus erythematosus (LE) specific, where the lesional biopsy shows a unique pattern of mucosal change in LE, and LE nonspecific, where the ulcers and their histopathological findings can be found in other oral diseases. Here, the clinical manifestations, diagnosis and management of oral ulcers in JSLE patients are reviewed.

Item Type:	Article
Uncontrolled Keywords:	Humans, Oral Ulcer, Lupus Erythematosus, Systemic, Age of Onset, Adolescent, Child, Female, Male
Depositing User:	Symplectic Admin
Date Deposited:	19 May 2017 13:46
Last Modified:	19 Jan 2023 07:04
DOI:	10.1007/s40257-017-0286-9
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3007551