Walker, Lauren E ORCID: 0000-0002-3827-4387, Janigro, Damir, Heinemann, Uwe, Riikonen, Raili, Bernard, Christophe and Patel, Manisha
(2016)
WONOEP appraisal: Molecular and cellular biomarkers for epilepsy.
EPILEPSIA, 57 (9).
pp. 1354-1362.
Text
E:\publications\epilepsia biomarkers\v2_Walker_biomarkers_main document_references_clean.docx - Author Accepted Manuscript Download (187kB) |
Abstract
Peripheral biomarkers have myriad potential uses for treatment, prediction, prognostication, and pharmacovigilance in epilepsy. To date, no single peripheral biomarker has demonstrated proven effectiveness, although multiple candidates are in development. In this review, we discuss the major areas of focus including inflammation, blood-brain barrier dysfunction, redox alterations, metabolism, hormones and growth factors.
Item Type: | Article |
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Uncontrolled Keywords: | Inflammation, Blood-brain barrier, High mobility group box 1 (HMGB1), S100B, brain derived neurotrophic factor, Insulin-like growth factor |
Depositing User: | Symplectic Admin |
Date Deposited: | 04 Sep 2017 14:11 |
Last Modified: | 19 Jan 2023 06:56 |
DOI: | 10.1111/epi.13460 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3009291 |