WONOEP appraisal: Molecular and cellular biomarkers for epilepsy



Walker, Lauren E ORCID: 0000-0002-3827-4387, Janigro, Damir, Heinemann, Uwe, Riikonen, Raili, Bernard, Christophe and Patel, Manisha
(2016) WONOEP appraisal: Molecular and cellular biomarkers for epilepsy. EPILEPSIA, 57 (9). pp. 1354-1362.

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Abstract

Peripheral biomarkers have myriad potential uses for treatment, prediction, prognostication, and pharmacovigilance in epilepsy. To date, no single peripheral biomarker has demonstrated proven effectiveness, although multiple candidates are in development. In this review, we discuss the major areas of focus including inflammation, blood-brain barrier dysfunction, redox alterations, metabolism, hormones and growth factors.

Item Type: Article
Uncontrolled Keywords: Inflammation, Blood-brain barrier, High mobility group box 1 (HMGB1), S100B, brain derived neurotrophic factor, Insulin-like growth factor
Depositing User: Symplectic Admin
Date Deposited: 04 Sep 2017 14:11
Last Modified: 19 Jan 2023 06:56
DOI: 10.1111/epi.13460
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3009291