Repurposing Statins for Renal Protection: Is It a Class Effect?

McWilliam, Stephen J ORCID: 0000-0002-0509-7425, Antoine, Daniel J and Pirmohamed, Munir ORCID: 0000-0002-7534-7266 (2018) Repurposing Statins for Renal Protection: Is It a Class Effect? CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 11 (2). pp. 100-102.

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Abstract

There has been a great deal of excitement regarding the potential benefits of statins beyond their lipid-lowering effect, and repurposing them for other indications. In this commentary, we evaluate the role of statins in protecting the kidneys, with a focus on three areas: cardiac surgery, contrast-induced nephropathy, and aminoglycoside-induced nephrotoxicity.

Item Type:	Article
Uncontrolled Keywords:	Kidney, Humans, Postoperative Complications, Aminoglycosides, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Protective Agents, Anti-Bacterial Agents, Contrast Media, Treatment Outcome, Cardiac Surgical Procedures, Randomized Controlled Trials as Topic, Acute Kidney Injury, Drug Repositioning
Depositing User:	Symplectic Admin
Date Deposited:	21 Nov 2017 14:49
Last Modified:	19 Jan 2023 06:50
DOI:	10.1111/cts.12521
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3012627