Acceptorless Dehydrogenative Oxidation of Secondary Alcohols Catalysed by Cp*Ir<SUP>III</SUP>-NHC Complexes



Gulcemal, Suleyman, Gulcemal, Derya, Whitehead, George FS and Xiao, Jianliang ORCID: 0000-0003-2010-247X
(2016) Acceptorless Dehydrogenative Oxidation of Secondary Alcohols Catalysed by Cp*Ir<SUP>III</SUP>-NHC Complexes. CHEMISTRY-A EUROPEAN JOURNAL, 22 (30). pp. 10513-10522.

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Abstract

A series of new Ir(III) complexes with carbene ligands that contain a range of benzyl wingtip groups have been prepared and fully characterised by NMR spectroscopy, HRMS, elemental analysis and X-ray diffraction. All the complexes were active in the acceptorless dehydrogenation of alcohol substrates in 2,2,2-trifluoroethanol to give the corresponding carbonyl compounds. The most active complex bore an electron-rich carbene ligand; this complex was used to catalyse the highly efficient and chemoselective dehydrogenation of a wide range of secondary alcohols to their respective ketones, with turnover numbers up to 1660. Mechanistic studies suggested that the turnover of the dehydrogenation reaction is limited by the H2 -formation step.

Item Type: Article
Uncontrolled Keywords: acceptorless dehydrogenation, alcohols, carbenes, iridium, oxidation
Depositing User: Symplectic Admin
Date Deposited: 22 Feb 2018 16:35
Last Modified: 05 Oct 2023 09:26
DOI: 10.1002/chem.201601648
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3018291