Evaluation of antihypertensive adherence and its determinants at primary healthcare facilities in rural South Africa

Rampamba, Enos M, Meyer, Johanna C, Godman, Brian ORCID: 0000-0001-6539-6972, Kurdi, Amanj and Helberg, Elvera (2018) Evaluation of antihypertensive adherence and its determinants at primary healthcare facilities in rural South Africa. JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH, 7 (7). pp. 661-672.

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Abstract

<h4>Aim</h4>To evaluate adherence to antihypertensive treatment in rural South Africa and identify potential determinants given concerns with adherence and its impact in this priority disease area. Patients & methods: Face-to-face interviews with hypertensive patients and rating their adherence to treatment using defined categorized responses. Associations between adherence and patient characteristics assessed and sensitivity analyses performed.<h4>Results</h4>54.6% of patients were adherent to treatment. Controlled blood pressure (BP; odds ratios [OR] = 2.1; 95% CI: 1.1, 3.8; p = 0.019), comorbidity (OR = 2.0; 95% CI: 1.1, 3.6; p = 0.032) and smoking (OR = 0.3; 95% CI: 0.1, 0.8; p = 0.018) were associated with adherence.<h4>Conclusion</h4>Adherence and BP control were suboptimal, only smoking was an independent risk factor for adherence. Adherent patients were twice as likely to have controlled BP, although results were sensitive to the definition of adherence. Initiatives are in place to improve adherence, which will be monitored.

Item Type:	Article
Uncontrolled Keywords:	adherence, hypertensive patients, South Africa
Depositing User:	Symplectic Admin
Date Deposited:	30 Jul 2018 09:19
Last Modified:	21 Feb 2023 06:56
DOI:	10.2217/cer-2018-0004
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3024302