Total anomalous pulmonary venous connection in a mature dog

Bode, EF ORCID: 0000-0003-3754-6026, Longo, M, Breheny, C, Culshaw, GJ and Martinez-Pereira, Y (2019) Total anomalous pulmonary venous connection in a mature dog. Journal of Veterinary Cardiology, 21. pp. 10-17.

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Abstract

A 2-year 10-month, male neutered, crossbreed dog presented for evaluation of cyanosis and exercise intolerance. Doppler echocardiography revealed severe dilation of the right atrium and right ventricle with moderate pulmonary hypertension. Right-to-left shunting across a large ostium secundum atrial septal defect was confirmed by contrast echocardiography. Thoracic radiography revealed a vascular pattern together with cardiomegaly. Computed tomography angiography identified an anomalous pulmonary venous connection in which all pulmonary veins, apart from the right middle vein, coalesced into a single, large aneurysmal vein that then drained into the right atrium via the cranial vena cava. The distal opening of the right middle pulmonary vein could not be determined. A presumptive diagnosis of partial anomalous pulmonary venous connection was made. The dog was medically managed with sildenafil (1.5 mg/kg by mouth [PO] every 8 h) and remained clinically stable for 2 months before euthanasia due to worsening exercise intolerance. On postmortem examination, all pulmonary veins, including the right middle vein, were shown to communicate with a single, large central vein. This large vein then connected with the right atrium via the cranial vena cava, consistent with a total anomalous pulmonary venous connection. This case report describes a rare congenital abnormality which has not been previously reported in a mature dog.

Item Type:	Article
Uncontrolled Keywords:	Cyanosis, Pulmonary hypertension, Ostium secundum atrial septal defect, Congenital cardiovascular defects
Depositing User:	Symplectic Admin
Date Deposited:	15 Oct 2018 10:01
Last Modified:	20 Jan 2023 12:00
DOI:	10.1016/j.jvc.2018.11.003
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3027486