Gastric carcinoma in canines and humans, a review

Hugen, S, Thomas, RE, German, AJ ORCID: 0000-0002-3017-7988, Burgener, IA and Mandigers, PJJ (2017) Gastric carcinoma in canines and humans, a review. VETERINARY AND COMPARATIVE ONCOLOGY, 15 (3). pp. 692-705.

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Abstract

Gastric carcinoma (GC) is the most common neoplasm in the stomach of dogs. Although incidence in the general population is reported to be low, breed-specific GC has a high incidence. Median age at presentation ranges from 8 to approximately 10 years. The disease is mostly located in the lesser curvature and antropyloric region of the stomach. Unfortunately, diagnosis is usually made when the disease is at an advanced stage and, therefore, prognosis is poor. Due to similarities in clinical presentation, diagnosis, histology and prognosis, canine GC may serve as a valuable model for human GC. Extensive pedigrees of canine gastric carcinoma cases could reveal insights for human gastric carcinoma. Putative species differences include the role of Helicobacter in pathogenesis, the wide array of genetic data and screening available for humans, and treatment protocols that are available for human GC.

Item Type:	Article
Uncontrolled Keywords:	clinical pathology, comparative oncology, genetics, pathology, small animal
Depositing User:	Symplectic Admin
Date Deposited:	25 Jan 2019 11:23
Last Modified:	19 Jan 2023 01:08
DOI:	10.1111/vco.12249
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3030729

Available Versions of this Item

• Gastric carcinoma in canines and humans, a review. (deposited 27 May 2016 07:53)
  • Gastric carcinoma in canines and humans, a review. (deposited 25 Jan 2019 11:23) [Currently Displayed]