Janot, Christopher, Palamini, Pierre, Dobson, Benjamin C, Muir, James and Aissa, Christophe ORCID: 0000-0003-0750-9435
(2019)
Palladium-Catalyzed Synthesis of Bis-Substituted Sulfoxonium Ylides.
ORGANIC LETTERS, 21 (1).
pp. 296-299.
Text
Palladium-catalyzed cross-coupling sulfoxonium-ylides - Elements.pdf - Author Accepted Manuscript Download (710kB) |
Abstract
The lack of general access to bis-substituted sulfoxonium ylides is addressed by developing a palladium-catalyzed C-H cross-coupling of α-ester sulfoxonium ylides with (hetero)aryl iodides, bromides, and triflates. Three different catalysts have been evaluated. This method is amenable to the late-stage functionalization of active pharmaceutical ingredients.
Item Type: | Article |
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Depositing User: | Symplectic Admin |
Date Deposited: | 25 Jan 2019 10:17 |
Last Modified: | 19 Jan 2023 01:08 |
DOI: | 10.1021/acs.orglett.8b03744 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3030783 |