Eimre, Margus, Kasvandik, Sergo, Ivask, Marilin and Koks, Sulev 
ORCID: 0000-0001-6087-6643
(2018)
Proteomic dataset of wolframin-deficient mouse heart and skeletal muscles.
DATA IN BRIEF, 21.
pp. 616-619.
Abstract
The data presented in this article are related to the research article entitled "Increased Mitochondrial Protein Levels and Bioenergetics in the <i>musculus rectus femoris</i> of Wfs1-Deficient mice" (Eimre et al., accepted for publication). This dataset reports the analysis of Wfs1-deficient mouse heart, <i>musculus soleus</i>, and white part of <i>musculus rectus femoris</i> by liquid chromatography/tandem mass spectrometry. Label-free quantitative analysis of the mass spectrometry data identified 4056 proteins, with 114, 212, and 1290 proteins differentially expressed (<i>t</i>-test; <i>p</i> < 0.05) in the heart, <i>m</i>. <i>soleus</i>, and <i>m. rectus femoris</i>, respectively, between the Wfs1-deficient and wild-type groups. Eight proteins were found to be differentially expressed in all mentioned muscles, with 1 protein differently expressed in oxidative (<i>m. soleus</i> and heart) and 88 in skeletal muscles. This dataset supports the cited study and can be used to extend additional analyses. Data are available via ProteomeXchange with identifier PXD011019.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Wolfram syndrome, Wfs1, Myocardium, skeletal muscle, Animal proteomics |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 01 Feb 2019 09:08 |
| Last Modified: | 19 Jan 2023 01:05 |
| DOI: | 10.1016/j.dib.2018.10.015 |
| Open Access URL: | https://doi.org/10.1016/j.dib.2018.10.015 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3032101 |
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