Eyers, Patrick A ORCID: 0000-0002-9220-2966
(2018)
A new consensus for evaluating CDKL5/STK9-dependent signalling mechanisms.
EMBO JOURNAL, 37 (24).
e100848-.
Text
A new consensus for evaluating CDKL5/STK9-dependent signalling mechanisms.pdf - Published version Download (281kB) | Preview |
Abstract
Mutation or inactivation of CDKL5 kinase is associated with a human neurodevelopmental condition commonly referred to as CDKL5 deficiency disorder.§ Two recent phosphoproteomics studies identify the first physiological substrates of mammalian CDKL5 and evaluate functional consequences of their phosphorylation and its loss in cells lacking functional CDKL5, highlighting potential roles for this kinase in regulating neuronal microtubule dynamics.
Item Type: | Article |
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Uncontrolled Keywords: | Microtubules, Animals, Humans, Spasms, Infantile, Signal Transduction, Phosphorylation, Epileptic Syndromes, Protein Serine-Threonine Kinases |
Depositing User: | Symplectic Admin |
Date Deposited: | 10 May 2019 09:08 |
Last Modified: | 25 Dec 2023 06:19 |
DOI: | 10.15252/embj.2018100848 |
Open Access URL: | http://10.0.59.148/embj.2018100848 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3040587 |