Fast Tracks and Roadblocks for Zika Vaccines

Ghaffar, Khairunnisa Abdul, Ng, Lisa FP ORCID: 0000-0003-4071-5222 and Renia, Laurent (2018) Fast Tracks and Roadblocks for Zika Vaccines. VACCINES, 6 (4). E77-.

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Official URL: http://dx.doi.org/10.3390/vaccines6040077

Abstract

In early 2014, a relatively obscure virus, the Zika virus, made headlines worldwide following an increase in the number of congenital malformations. Since then, research on Zika virus, treatment and vaccines have progressed swiftly with various drugs being repurposed and vaccines heading into clinical trials. Nonetheless, the need for a vaccine is crucial in order to eradicate this re-emerging arthropod-borne virus which remained silent since its first discovery in 1947. In this review, we focused on how the inconspicuous virus managed to spread, the key immunological factors required for a vaccine and the various vaccine platforms that are currently being studied.

Item Type:	Article
Uncontrolled Keywords:	Zika virus, vaccine, immune responses, delivery systems
Depositing User:	Symplectic Admin
Date Deposited:	14 May 2019 10:34
Last Modified:	19 Jan 2023 00:45
DOI:	10.3390/vaccines6040077
Open Access URL:	https://doi.org/10.3390/vaccines6040077
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3041244