Lord, Rachel, George, Keith, Somauroo, John, Stembridge, Mike, Jain, Nikhil, Hoffman, Martin D, Shave, Rob, Haddad, Francois, Ashley, Euan, Jones, Helen et al (show 1 more authors)
(2016)
Alterations in Cardiac Mechanics Following Ultra-Endurance Exercise: Insights from Left and Right Ventricular Area-Deformation Loops.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 29 (9).
879-+.
Abstract
<h4>Background</h4>The aim of this study was to use novel area-deformation (ε) loops to interrogate the interaction between the right ventricular (RV) and left ventricular (LV) mechanics following a 100-mile endurance run.<h4>Methods</h4>Fifteen participants (mean body mass, 70.1 ± 8.8 kg; mean age, 40 ± 8 years) were recruited for the study. Echocardiography was performed before the race, after the race, and 6 hours into recovery. RV and LV area and longitudinal ε were assessed using standard and speckle-tracking echocardiography. Following cubic spline interpolation, these variables were obtained across the same cardiac cycle and used to derive area-ε loops.<h4>Results</h4>The RV area-ε loop demonstrated a rightward shift after the race, with increased RV area (from 26.0 to 27.1 cm(2)) and reduced peak RV ε (from -28.6% to -25.8%). The recovery RV area-ε loop was similar to the postrace loop. A leftward shift was observed in the LV area-ε loop after the race, secondary to reduced LV area (from 35.8 to 32.5 cm(2)) and reduced peak ε (from -18.3% to -16.6%). In recovery, LV ε values returned toward baseline.<h4>Conclusions</h4>A 100-mile ultramarathon resulted in a rightward shift in the RV area-ε loop as a result of RV dilatation. There was a concomitant leftward shift in the LV area-ε loop as a result of underfilling of the left ventricle. At 6 hours after exercise, there was a partial recovery of the left ventricle, while RV function remained depressed. It appears that changes in RV function do not have a serial impact on the left ventricle during recovery from ultra-endurance activity.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Echocardiography, Endurance exercise, Strain imaging, Area-deformation loops, Cardiac mechanics |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 21 May 2019 10:48 |
| Last Modified: | 19 Jan 2023 00:43 |
| DOI: | 10.1016/j.echo.2016.05.004 |
| Open Access URL: | http://researchonline.ljmu.ac.uk/id/eprint/3867/ |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3042295 |
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