Adler, Hugh, Nikolaou, Elissavet, Gould, Katherine, Hinds, Jason, Collins, Andrea M, Connor, Victoria, Hales, Caz, Hill, Helen, Hyder-Wright, Angela D, Zaidi, Seher R et al (show 8 more authors)
(2019)
Pneumococcal colonization in healthy adult research participants in the conjugate vaccine era, United Kingdom, 2010-2017.
The Journal of infectious diseases, 219 (12).
pp. 1989-1993.
Text
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Abstract
Pneumococcal colonization is rarely studied in adults, except as part of family surveys. We report the outcomes of colonization screening in healthy adults (non-smokers without major comorbidities or contact with children under five years) who had volunteered to take part in clinical research. Using nasal wash culture, we detected colonization in 6.5% (52/795) of volunteers. Serotype 3 was the commonest serotype (10/52). The majority of the remainder (35/52) were non-vaccine serotypes, but we also identified persistent circulation of serotypes 19A and 19F. Resistance to at least one of six antibiotics tested was found in 8/52 isolates.
Item Type: | Article |
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Uncontrolled Keywords: | Drug resistance, microbial, herd immunity, nasal washing, Streptococcus pneumoniae |
Depositing User: | Symplectic Admin |
Date Deposited: | 31 May 2019 10:34 |
Last Modified: | 19 Jan 2023 00:41 |
DOI: | 10.1093/infdis/jiz034 |
Open Access URL: | https://doi.org/10.1093/infdis/jiz034 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3043832 |