Growth Patterns of Residual Tumor in Preoperatively Growing Vestibular Schwannomas



Kasbekar, Anand V, Adan, Guleed H ORCID: 0000-0001-7340-4207, Beacall, Alaina, Youssef, Ahmed M, Gilkes, Catherine E and Lesser, Tristram H
(2018) Growth Patterns of Residual Tumor in Preoperatively Growing Vestibular Schwannomas. JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE, 79 (4). pp. 319-324.

[img] Text
Growth Patterns of Residual Tumor in.pdf - Published version

Download (174kB) | Preview

Abstract

<b>Objectives</b>  To analyze growth of residual vestibular schwannoma (VS) following incomplete tumor resection and determine the influence of residual location and size. <b>Design</b>  Retrospective case note and scan review. <b>Setting</b>  Tertiary skull base unit. <b>Participants</b>  Patients with residual tumor following primary surgery for medium and large unilateral growing vestibular schwanomas between 2006 and 2009. <b>Main Outcome Measures</b>  Location of residual VS and post-operative growth, comparing those with more (>5%) or less than 5% of tumor residual (<5%). <b>Results</b>  Fifty-two patients had visible residual tumor left behind at surgery. Twenty had < 5% and 32 had > 5% residual. The residual growth rates were 38% overall, 20% in < 5%, and 50% in > 5% residuals. There was no significant difference in growth rates at different residual locations. Median follow-up was 6.4 years. <b>Conclusions</b>  There is a greater risk of regrowth of residuals > 5%. All positions of residual tumor can regrow, and the preoperative tumor size plays a role in this. Further data is needed to confirm if residual tumor in the fundus is less likely to grow.

Item Type: Article
Uncontrolled Keywords: vestibular schwannoma, residual tumor, tumor regrowth
Depositing User: Symplectic Admin
Date Deposited: 24 Feb 2020 14:43
Last Modified: 19 Jan 2023 00:40
DOI: 10.1055/s-0037-1607421
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3045282