Metagenomics in ophthalmology: current findings and future prospectives

Borroni, Davide ORCID: 0000-0001-6952-5647, Romano, Vito ORCID: 0000-0002-5148-7643, Kaye, Stephen B ORCID: 0000-0003-0390-0592, Somerville, Tobi, Napoli, Luca, Fasolo, Adriano, Gallon, Paola, Ponzin, Diego, Esposito, Alfonso and Ferrari, Stefano (2019) Metagenomics in ophthalmology: current findings and future prospectives. BMJ OPEN OPHTHALMOLOGY, 4 (1). e000248-.

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Official URL: http://dx.doi.org/10.1136/bmjophth-2018-000248

Abstract

Less than 1% of all microorganisms of the available environmental microbiota can be cultured with the currently available techniques. Metagenomics is a new methodology of high-throughput DNA sequencing, able to provide taxonomic and functional profiles of microbial communities without the necessity to culture microbes in the laboratory. Metagenomics opens to a 'hypothesis-free' approach, giving important details for future research and treatment of ocular diseases in ophthalmology, such as ocular infection and ocular surface diseases.

Item Type:	Article
Uncontrolled Keywords:	cornea, eye, metagenomics, microbiome, ocular surface, ophthalmology, sequencing
Depositing User:	Symplectic Admin
Date Deposited:	07 Aug 2019 09:11
Last Modified:	19 Jan 2023 00:36
DOI:	10.1136/bmjophth-2018-000248
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3051179