Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017



Smith, Toby O, Mansfield, Michael, Hawker, Gillian A, Hunter, David J, March, Lyn M, Boers, Maarten, Shea, Beverley J, Christensen, Robin, Guillemin, Francis, Terwee, Caroline B
et al (show 18 more authors) (2019) Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017. JOURNAL OF RHEUMATOLOGY, 46 (8). pp. 976-980.

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Abstract

<h4>Objective</h4>To assess the uptake of the OMERACT-OARSI (Outcome Measures in Rheumatology- Osteoarthritis Research Society International) core outcome set (COS) domains in hip and/or knee osteoarthritis (OA) trials.<h4>Methods</h4>There were 382 trials of hip and/or knee OA identified from the ClinicalTrial.gov registry from 1997 to 2017. Frequency of COS adoption was assessed by year and per 5-yearly phases.<h4>Results</h4>COS adoption decreased from 61% between 1997 and 2001 to 38% between 2012 and 2016. Pain (95%) and physical function (86%) were most consistently adopted. Patient's global assessment (48%) was the principal missing domain.<h4>Conclusion</h4>Limited adoption of the COS domains indicates that further consideration to improve uptake is required.

Item Type: Article
Uncontrolled Keywords: OMERACT, CORE OUTCOME SET, DOMAIN, ADOPTION, TRIAL REGISTRATION
Depositing User: Symplectic Admin
Date Deposited: 28 Oct 2019 10:48
Last Modified: 20 Sep 2023 20:07
DOI: 10.3899/jrheum.181066
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3059431