Hill, Jason, Rastas, Pasi, Hornett, Emily A, Neethiraj, Ramprasad, Clark, Nathan, Morehouse, Nathan, Celorio-Mancera, Maria De La Paz, Carnicer, Jofre, Dircksen, Heinrich, Meslin, Camille et al (show 10 more authors)
(2019)
Unprecedented reorganization of holocentric chromosomes provides insights into the enigma of lepidopteran chromosome evolution.
SCIENCE ADVANCES, 5 (6).
eaau3648-.
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Unprecedented reorganization of holocentric chromosomes provides insights into the enigma of lepidopteran chromosome evoluti.pdf - Published version Download (3MB) | Preview |
Abstract
Chromosome evolution presents an enigma in the mega-diverse Lepidoptera. Most species exhibit constrained chromosome evolution with nearly identical haploid chromosome counts and chromosome-level gene collinearity among species more than 140 million years divergent. However, a few species possess radically inflated chromosomal counts due to extensive fission and fusion events. To address this enigma of constraint in the face of an exceptional ability to change, we investigated an unprecedented reorganization of the standard lepidopteran chromosome structure in the green-veined white butterfly (<i>Pieris napi</i>). We find that gene content in <i>P. napi</i> has been extensively rearranged in large collinear blocks, which until now have been masked by a haploid chromosome number close to the lepidopteran average. We observe that ancient chromosome ends have been maintained and collinear blocks are enriched for functionally related genes suggesting both a mechanism and a possible role for selection in determining the boundaries of these genome-wide rearrangements.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Animals, Butterflies, Bombyx, Chromosome Mapping, Evolution, Molecular, Phylogeny, Ploidies, Female, Male, Genome, Insect, Selection, Genetic, Genetic Linkage, Chromosomes, Insect, Genome Size |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 28 Nov 2019 17:00 |
| Last Modified: | 19 Jan 2023 00:18 |
| DOI: | 10.1126/sciadv.aau3648 |
| Open Access URL: | https://doi.org/10.1126/sciadv.aau3648 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3063896 |
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