THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors.



Alexander, Stephen PH ORCID: 0000-0003-4417-497X, Fabbro, Doriano ORCID: 0000-0002-9400-4517, Kelly, Eamonn, Mathie, Alistair ORCID: 0000-0001-6094-2890, Peters, John A ORCID: 0000-0002-4277-4245, Veale, Emma L ORCID: 0000-0002-6778-9929, Armstrong, Jane F ORCID: 0000-0002-0524-0260, Faccenda, Elena ORCID: 0000-0001-9855-7103, Harding, Simon D ORCID: 0000-0002-9262-8318, Pawson, Adam J ORCID: 0000-0003-2280-845X
et al (show 4 more authors) (2019) THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors. British journal of pharmacology, 176 Su (Suppl ). S247-S296.

Access the full-text of this item by clicking on the Open Access link.
[img] Text
THE CONCISE GUIDE TO PHARMACOLOGY 201920 Catalytic receptors.pdf - Published version

Download (1MB) | Preview

Abstract

The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14751. Catalytic receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

Item Type: Article
Uncontrolled Keywords: CGTP Collaborators, Animals, Humans, Peptides, Receptors, Cell Surface, Ligands, Databases, Pharmaceutical
Depositing User: Symplectic Admin
Date Deposited: 21 Feb 2020 16:01
Last Modified: 19 Jan 2023 00:10
DOI: 10.1111/bph.14751
Open Access URL: https://doi.org/10.1111/bph.14751
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3069647