Myopericarditis as a presentation of eosinophilic granulomatosus with polyangiitis (EGPA)

Dey, Mrinalini ORCID: 0000-0001-6858-4338, Nair, Jagdish, Sankaranarayanan, Rajiv ORCID: 0000-0003-2355-2011 and Kanagala, Prathap ORCID: 0000-0001-6739-5607 (2019) Myopericarditis as a presentation of eosinophilic granulomatosus with polyangiitis (EGPA). BMJ CASE REPORTS, 12 (8). e230593-.

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Abstract

A 60-year-old woman was admitted to the hospital with worsening dyspnoea, cough and chest pain. This was on a background of weight loss, decreased appetite, mononeuritis multiplex, chronic eosinophilia and a single episode of a non-blanching rash. Investigations demonstrated a raised troponin and ischaemic changes on ECG, and she was therefore initially treated for a presumed myocardial infarction. However, her symptoms failed to improve with treatment for the acute coronary syndrome. A coronary angiogram revealed no significant flow-limiting disease, and further investigations yielded confirmation of raised eosinophils and a positive perinuclear antineutrophil cytoplasmic antibody test. An echocardiogram demonstrated a pericardial effusion, and subsequent cardiac magnetic resonance features were compatible with myopericarditis. In light of these findings, the patient was diagnosed with eosinophilic granulomatous with polyangiitis and commenced on high-dose intravenous methylprednisolone and cyclophosphamide. She made an excellent recovery and remains in remission on azathioprine and a tapering dose of corticosteroids.

Item Type:	Article
Uncontrolled Keywords:	pericardial disease, vasculitis
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Clinical Directorate
Depositing User:	Symplectic Admin
Date Deposited:	20 Oct 2022 10:29
Last Modified:	20 Mar 2023 09:44
DOI:	10.1136/bcr-2019-230593
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3073735