Is reduction in appetite beneficial for body weight management in the context of overweight and obesity? Yes, according to the SATIN (Satiety Innovation) study



Hansen, Thea Toft, Mead, Bethan R ORCID: 0000-0002-9294-517X, Francisco Garcia-Gavilan, Jesus, Korndal, Sanne Kellebjerg, Harrold, Joanne A ORCID: 0000-0002-0899-4586, Camacho-Barcia, Lucia, Ritz, Christian, Christiansen, Paul, Salas-Salvado, Jordi, Hjorth, Mads Fiil
et al (show 4 more authors) (2019) Is reduction in appetite beneficial for body weight management in the context of overweight and obesity? Yes, according to the SATIN (Satiety Innovation) study. JOURNAL OF NUTRITIONAL SCIENCE, 8. e39-.

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Abstract

New dietary-based concepts are needed for treatment and effective prevention of overweight and obesity. The primary objective was to investigate if reduction in appetite is associated with improved weight loss maintenance. This cohort study was nested within the European Commission project Satiety Innovation (SATIN). Participants achieving ≥8% weight loss during an initial 8-week low-energy formula diet were included in a 12-week randomised double-blind parallel weight loss maintenance intervention. The intervention included food products designed to reduce appetite or matching controls along with instructions to follow national dietary guidelines. Appetite was assessed by <i>ad libitum</i> energy intake and self-reported appetite evaluations using visual analogue scales during standardised appetite probe days. These were evaluated at the first day of the maintenance period compared with baseline (acute effects after a single exposure of intervention products) and post-maintenance compared with baseline (sustained effects after repeated exposures of intervention products) regardless of randomisation. A total of 181 participants (forty-seven men and 134 women) completed the study. Sustained reduction in 24-h energy intake was associated with improved weight loss maintenance (<i>R</i> 0·37; <i>P</i> = 0·001), whereas the association was not found acutely (<i>P</i> = 0·91). Suppression in self-reported appetite was associated with improved weight loss maintenance both acutely (<i>R</i> -0·32; <i>P</i> = 0·033) and sustained (<i>R</i> -0·33; <i>P</i> = 0·042). Reduction in appetite seems to be associated with improved body weight management, making appetite-reducing food products an interesting strategy for dietary-based concepts.

Item Type: Article
Uncontrolled Keywords: Satiety, Hunger, Food innovation, Weight loss, Weight maintenance
Depositing User: Symplectic Admin
Date Deposited: 07 Feb 2020 15:53
Last Modified: 25 Jan 2024 10:12
DOI: 10.1017/jns.2019.36
Open Access URL: https://www.cambridge.org/core/journals/journal-of...
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3073996