Microevolution and Patterns of Transmission of <i>Shigella sonnei</i> within Cyclic Outbreaks of Shigellosis, Israel



Behar, Adi, Baker, Kate Susan ORCID: 0000-0001-5850-1949, Bassal, Ravit, Ezernitchi, Analia, Valinsky, Lea, Thomson, Nicholas R and Cohen, Daniel
(2018) Microevolution and Patterns of Transmission of <i>Shigella sonnei</i> within Cyclic Outbreaks of Shigellosis, Israel. EMERGING INFECTIOUS DISEASES, 24 (7). pp. 1335-1339.

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Abstract

Whole-genome sequencing unveiled host and environment-related insights to Shigella sonnei transmission within cyclic epidemics during 2000-2012 in Israel. The Israeli reservoir contains isolates belonging to S. sonnei lineage III but of different origin, shows loss of tetracycline resistance genes, and little genetic variation within the O antigen: highly relevant for Shigella vaccine development.

Item Type: Article
Uncontrolled Keywords: Humans, Shigella sonnei, Dysentery, Bacillary, Disease Outbreaks, Evolution, Molecular, Genome, Bacterial, Israel, Public Health Surveillance, Whole Genome Sequencing
Depositing User: Symplectic Admin
Date Deposited: 19 Feb 2020 11:09
Last Modified: 13 Oct 2023 03:01
DOI: 10.3201/eid2407.171313
Open Access URL: https://wwwnc.cdc.gov/eid/article/24/7/17-1313_art...
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URI: https://livrepository.liverpool.ac.uk/id/eprint/3075702