Chiral cyclometalated iridium complexes for asymmetric reduction reactions.

Smith, Jennifer, Kacmaz, Aysecik, Wang, Chao, Villa-Marcos, Barbara and Xiao, Jianliang ORCID: 0000-0003-2010-247X (2020) Chiral cyclometalated iridium complexes for asymmetric reduction reactions. Organic & biomolecular chemistry, 19 (1). pp. 279-284.

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Official URL: http://dx.doi.org/10.1039/d0ob02049d

Abstract

A series of chiral cyclometalated iridium complexes have been synthesised by cyclometalating chiral 2-aryl-oxazoline and imidazoline ligands with [Cp*IrCl2]2. These iridacycles were studied for asymmetric transfer hydrogenation reactions with formic acid as the hydrogen source and were found to display various activities and enantioselectivities, with the most effective ones affording up to 63% ee in the asymmetric reductive amination of ketones and 77% ee in the reduction of pyridinium ions.

Item Type:	Article
Depositing User:	Symplectic Admin
Date Deposited:	30 Nov 2020 09:25
Last Modified:	18 Jan 2023 23:20
DOI:	10.1039/d0ob02049d
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3108509