The chronic myeloid leukaemia story in the United Kingdom since 1960

Clark, Richard E ORCID: 0000-0002-1261-3299 (2020) The chronic myeloid leukaemia story in the United Kingdom since 1960. BRITISH JOURNAL OF HAEMATOLOGY, 191 (4). pp. 521-526.

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Official URL: http://dx.doi.org/10.1111/bjh.17149

Abstract

Over the past 60 years, haematologists and scientists from the United Kingdom, notably John Goldman and Tessa Holyoake, have punched above their weight in changing chronic myeloid leukaemia (CML) from an incurable and invariably fatal disease for all, to a chronic condition where over 90% have normal life expectancy. As a result, it is now difficult to power a worthwhile phase 3 study for newly diagnosed patients. Nevertheless, important clinical questions remain.

Item Type:	Article
Uncontrolled Keywords:	Chronic myeloid leukaemia, CML, Philadelphia translocation, BCR&#8208, ABL, imatinib, tyrosine kinase inhibitors
Depositing User:	Symplectic Admin
Date Deposited:	14 Jan 2021 09:35
Last Modified:	07 Sep 2023 02:41
DOI:	10.1111/bjh.17149
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3112548