Harky, Amer 
ORCID: 0000-0001-5507-5841, Fok, Matthew ORCID: 0000-0003-4091-6569 and Bashir, Mohamad
(2020)
Which is the Optimal Frozen Elephant Trunk? A Systematic Review and Meta-Analysis of Outcomes in 2161 Patients Undergoing Thoracic Aortic Aneurysm Surgery Using E-vita OPEN PLUS Hybrid Stent Graft versus Thoraflex (TM) Hybrid Prosthesis.
BRAZILIAN JOURNAL OF CARDIOVASCULAR SURGERY, 35 (4).
pp. 427-436.
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Abstract
<h4>Objective</h4>To systematically review the rate of morbidity and mortality associated with the use of E-vita hybrid stent graft and ThoraflexTM in patients undergoing complex aortic surgery.<h4>Methods</h4>A comprehensive search was undertaken among the four major databases to identify published data about E-vita or Thoraflex™ in patients undergoing repair of thoracic aortic aneurysms.<h4>Results</h4>In total, 28 papers were included in the study, encompassing a total of 2,161 patients (1,919 E-vita and 242 Thoraflex™). Patients undergoing surgery with E-vita or Thoraflex™ were of similar age and sex. The number of patients undergoing non-elective repair with Thoraflex™ was higher than with E-vita (35.2% vs. 28.7%, respectively). Cardiopulmonary bypass time was associated with increasing mortality in E-vita patients, however a meta-analysis of proportions showed higher 30-day mortality, permanent neurological deficit, and one-year mortality for Thoraflex™ patients. Direct statistical comparisons between E-vita and Thoraflex™ was not possible due to heterogeneity of studies.<h4>Conclusion</h4>Although there are limited studies available, the available data suggests that mortality and morbidity are lower for the E-vita device in thoracic aortic aneurysm surgery than for Thoraflex™. Long-term data of comparative studies do not yet exist to assess viability of these procedures.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Aortic Aneurysm, Thoracic, Tocopherols, Cardiopulmonary Bypass, Stents, Morbidity |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 15 Feb 2021 10:40 |
| Last Modified: | 18 Jan 2023 23:00 |
| DOI: | 10.21470/1678-9741-2019-0220 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3115667 |
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