Epidemiology of Atrial Fibrillation: Geographic/Ecological Risk Factors, Age, Sex, Genetics.

Zhang, Juqian ORCID: 0000-0002-9653-8635, Johnsen, Søren Paaske, Guo, Yutao and Lip, Gregory YH ORCID: 0000-0002-7566-1626 (2021) Epidemiology of Atrial Fibrillation: Geographic/Ecological Risk Factors, Age, Sex, Genetics. Cardiac Electrophysiology Clinics, 13 (1). pp. 1-23.

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Abstract

Atrial fibrillation is the most common arrhythmia globally. The global prevalence of atrial fibrillation is positively correlated with the sociodemographic index of different regions. Advancing age, male sex, and Caucasian race are risk factors; female sex is correlated with higher atrial fibrillation mortality worldwide likely owing to thromboembolic risk. African American ethnicity is associated with lower atrial fibrillation risk, same as Asian and Hispanic/Latino ethnicities compared with Caucasians. Atrial fibrillation may be heritable, and more than 100 genetic loci have been identified. A polygenic risk score and clinical risk factors are feasible and effective in risk stratification of incident disease.

Item Type:	Article
Uncontrolled Keywords:	Humans, Atrial Fibrillation, Genetic Predisposition to Disease, Risk Factors, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	19 Mar 2021 08:05
Last Modified:	18 Jan 2023 22:55
DOI:	10.1016/j.ccep.2020.10.010
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3117656