Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter?

Nabrdalik, Katarzyna, Krzyzak, Katarzyna, Hajzler, Weronika, Drozdz, Karolina, Kwiendacz, Hanna, Gumprecht, Janusz and Lip, Gregory YH ORCID: 0000-0002-7566-1626 (2021) Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter? NUTRIENTS, 13 (2). 639-.

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Official URL: http://dx.doi.org/10.3390/nu13020639

Abstract

The incidence of cardiometabolic diseases, such as obesity, diabetes, and cardiovascular diseases, is constantly rising. Successful lifestyle changes may limit their incidence, which is why researchers focus on the role of nutrition in this context. The outcomes of studies carried out in past decades have influenced dietary guidelines, which primarily recommend reducing saturated fat as a therapeutic approach for cardiovascular disease prevention, while limiting the role of sugar due to its harmful effects. On the other hand, a low-carbohydrate diet (LCD) as a method of treatment remains controversial. A number of studies on the effect of LCDs on patients with type 2 diabetes mellitus proved that it is a safe and effective method of dietary management. As for the risk of cardiovascular diseases, the source of carbohydrates and fats corresponds with the mortality rate and protective effect of plant-derived components. Additionally, some recent studies have focused on the gut microbiota in relation to cardiometabolic diseases and diet as one of the leading factors affecting microbiota composition. Unfortunately, there is still no precise answer to the question of which a single nutrient plays the most important role in reducing cardiometabolic risk, and this review article presents the current state of the knowledge in this field.

Item Type:	Article
Uncontrolled Keywords:	carbohydrates, diabetes mellitus, diet, fat, microbiota
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	29 Jun 2021 15:57
Last Modified:	18 Jan 2023 21:37
DOI:	10.3390/nu13020639
Open Access URL:	https://www.mdpi.com/2072-6643/13/2/639
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3128158