Prophylactic Corneal Cross-Linking in Myopic Femtosecond Laser-Assisted In Situ Keratomileusis: Long-Term Visual and Refractive Outcomes



Alonso-Aliste, Federico, Amián-Cordero, Jonatan, Rachwani-Anil, Rahul ORCID: 0000-0001-5901-2469, De-Hita-Cantalejo, Concepción, Borroni, Davide ORCID: 0000-0001-6952-5647, Rocha-de-Lossada, Carlos ORCID: 0000-0001-7464-2493 and Sánchez-González, José-María ORCID: 0000-0003-0450-7717
(2021) Prophylactic Corneal Cross-Linking in Myopic Femtosecond Laser-Assisted In Situ Keratomileusis: Long-Term Visual and Refractive Outcomes. Optics, 2 (1). pp. 55-62.

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Abstract

<jats:p>The purpose of our study was to evaluate the safety, effectiveness, predictability, and stability of myopic and astigmatic laser-assisted in situ keratomileusis (LASIK) with simultaneous prophylactic corneal cross-linking (CXL) in thin corneas. In total, 100 eyes from 50 patients who were subjected to myopic and astigmatism femtosecond LASIK with simultaneous prophylactic CXL were included. The design of the study was retrospective, longitudinal, and observational. All patients had a 48-month follow-up. The MEL 80 excimer laser was utilized with the Aberration Smart Ablation platform. CXL treatment was applied when the predicted stromal thickness was less than 330 µm. Patients’ mean age was 30.22 ± 5.97 years. Previous mean spherical equivalent was −5.50 ± 1.65 (−9.50 to −1.13) diopters (D). Postoperative mean spherical equivalent was −0.24 ± 0.29 (−0.85 to +0.50) D. Visual acuity (VA) of 20/20 or better was observed in 87% of the eyes and no eyes experienced VA loss. Spherical equivalent within ±0.50 D was observed in 93% of eyes, and 4% of eyes varied by 0.50 D or more between 3 and 48 months. Prophylactic corneal cross-linking with simultaneous femtosecond laser-assisted in situ keratomileusis in thin corneas proved to be effective, safe, and predictable. The results remained stable after 48 months of follow-up.</jats:p>

Item Type: Article
Uncontrolled Keywords: Eye Disease and Disorders of Vision, Eye
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 30 Jun 2021 13:57
Last Modified: 17 Mar 2024 11:30
DOI: 10.3390/opt2010006
Open Access URL: https://www.mdpi.com/2673-3269/2/1/6
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3128283