Thorn, Joanna C, Davies, Charlotte F, Brookes, Sara T, Noble, Sian M, Dritsaki, Melina, Gray, Ewan, Hughes, Dyfrig A ORCID: 0000-0001-8247-7459, Mihaylova, Borislava, Petrou, Stavros, Ridyard, Colin et al (show 4 more authors)
(2020)
Content of Health Economics Analysis Plans (HEAPs) for Trial-Based Economic Evaluations: Expert Delphi Consensus Survey.
VALUE IN HEALTH, 24 (4).
pp. 539-547.
Abstract
<h4>Objectives</h4>Health economics analysis plans (HEAPs) currently lack consistency, with uncertainty surrounding appropriate content. We aimed to develop a list of essential items that should be included in HEAPs for economic evaluations conducted alongside randomized trials.<h4>Methods</h4>A list of potential items for inclusion was developed by examining existing HEAPs. An electronic Delphi survey was conducted among professional health economists. Respondents were asked to rate potential items from 1 (least important) to 9 (most important), suggest additional items, and comment on proposed items (round 1). A second survey (round 2) was emailed to participants, including the participant's own scores from round 1 along with summary results from the whole panel; participants were asked to rerate each item. Consensus criteria for inclusion in the final list were predefined as >70% of participants rating an item 7-9 and <15% rating it 1-3 after round 2. A final item selection meeting was held to scrutinize the results and adjudicate on items lacking consensus.<h4>Results</h4>62 participants completed round 1 of the survey. The initial list included 72 potential items; all 72 were carried forward to round 2, and no new items were added. 48 round 1 respondents (77.4%) completed round 2 and reached consensus on 53 items. At the final meeting, the expert panel (n = 9) agreed that 58 items should be included in the essential list, moved 9 items to an optional list, and dropped 5 items.<h4>Conclusions</h4>Via expert consensus opinion, this study identified 58 items that are considered essential in a HEAP.
Item Type: | Article |
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Uncontrolled Keywords: | analysis plans, bias, economic evaluation |
Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology |
Depositing User: | Symplectic Admin |
Date Deposited: | 07 Jul 2021 10:11 |
Last Modified: | 18 Jan 2023 21:36 |
DOI: | 10.1016/j.jval.2020.10.002 |
Open Access URL: | https://doi.org/10.1016/j.jval.2020.10.002 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3129123 |