Fountain, Daniel M, Piper, Rory J, Poon, Michael TC, Solomou, Georgios, Brennan, Paul M, Chowdhury, Yasir A, Colombo, Francesca, Elmoslemany, Tarek, Ewbank, Frederick G, Grundy, Paul L et al (show 20 more authors)
(2021)
CovidNeuroOnc: A UK multicenter, prospective cohort study of the impact of the COVID-19 pandemic on the neuro-oncology service.
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Abstract
Background. The COVID-19 pandemic has profoundly affected cancer services. Our objective was to determine the effect of the COVID-19 pandemic on decision making and the resulting outcomes for patients with newly diagnosed or recurrent intracranial tumors. Methods. We performed a multicenter prospective study of all adult patients discussed in weekly neuro-oncology and skull base multidisciplinary team meetings who had a newly diagnosed or recurrent intracranial (excluding pituitary) tumor between 01 April and 31 May 2020. All patients had at least 30-day follow-up data. Descriptive statistical reporting was used. Results. There were 1357 referrals for newly diagnosed or recurrent intracranial tumors across 15 neuro-oncology centers. Of centers with all intracranial tumors, a change in initial management was reported in 8.6% of cases (n = 104/1210). Decisions to change the management plan reduced over time from a peak of 19% referrals at the start of the study to 0% by the end of the study period. Changes in management were reported in 16% (n = 75/466) of cases previously recommended for surgery and 28% of cases previously recommended for chemotherapy (n = 20/72). The reported SARS-CoV-2 infection rate was similar in surgical and non-surgical patients (2.6% vs. 2.4%, P > .9).
| Item Type: | Conference or Workshop Item (Unspecified) |
|---|---|
| Uncontrolled Keywords: | brain tumor, COVID-19, intracranial tumor, neurooncology, | SARS-CoV-2 |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Population Health |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 21 Jul 2021 09:11 |
| Last Modified: | 08 Feb 2023 19:47 |
| DOI: | 10.1093/noajnl/vdab014 |
| Open Access URL: | https://doi.org/10.1093/noajnl/vdab014 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3130804 |
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