Kimyongur, Selim, Hywel, Brython and Holt, James
(2019)
The use of IVIg in the treatment of inflammatory polyneuropathies and myasthenia gravis at The Walton Centre.
JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH, 49 (1).
pp. 5-11.
Abstract
<h4>Background</h4>Immunoglobulin is a blood product used in a variety of medical disorders, usually delivered intravenously (IVIg). Neurology patients, particularly those with inflammatory polyneuropathy, utilise a lot of IVIg. There is a national shortage of immunoglobulin and, thus, pressing need to ensure minimum effective dosing as well as rigorous outcome assessments to assess benefit at treatment start and subsequently, as placebo effects can be strong.<h4>Methods</h4>Serial audit of IVIg use at The Walton Centre against national guidelines was carried out through analysis of clinical notes of day unit patients. Review of the national immunoglobulin database and of neurology outpatient notes to benchmark our practice and provide some comparison with the wider nation was also performed.<h4>Results</h4>Serial audit led to improved adherence to guidelines, and analysis of practice identified wide variation in IVIg use.<h4>Conclusion</h4>Local audit and benchmarking of practice can be used to promote quality and consistency of IVIg use across the NHS.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CIDP immunoglobulin, IVIg, myasthenia gravis, polyneuropathy, treatment |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Clinical Directorate |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 01 Oct 2021 07:20 |
| Last Modified: | 07 Feb 2024 19:02 |
| DOI: | 10.4997/JRCPE.2019.102 |
| Open Access URL: | https://www.rcpe.ac.uk/college/journal/use-ivig-tr... |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3138838 |
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