Gue, Ying X 
ORCID: 0000-0001-9994-8915, Jeong, Young-Hoon, Farag, Mohamed, Spinthakis, Nikolaos and Gorog, Diana A
(2021)
Precision Treatment in ACS-Role of Assessing Fibrinolysis.
JOURNAL OF CLINICAL MEDICINE, 10 (5).
929-.
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Abstract
Despite advancements in pharmacotherapy and interventional strategies, patients with acute coronary syndrome (ACS) remain at risk of recurrent thrombotic events. In addition to an enhanced tendency to thrombus formation, impairment in the ability to naturally dissolve or lyse a developing thrombus, namely impaired endogenous fibrinolysis, is responsible for a major part of this residual risk regardless of optimal antiplatelet medication. Global assessment of endogenous fibrinolysis, including a point-of-care assay, can identify patients with ACS at persistent high cardiovascular risk and might play an important role in allowing the personalisation of potent antithrombotic therapy to enhance fibrinolytic status, providing precision treatment of ACS to improve long-term outcome.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | endogenous fibrinolysis, precision medicine, acute coronary syndrome |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 17 Dec 2021 16:45 |
| Last Modified: | 18 Jan 2023 21:18 |
| DOI: | 10.3390/jcm10050929 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3145597 |
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