Zhang, Juqian 
ORCID: 0000-0002-9653-8635, Bisson, Arnaud ORCID: 0000-0002-3449-1800, Boumhidi, Jad, Herbert, Julien, Saint Etienne, Christophe, Bernard, Anne, Lip, Gregory YH ORCID: 0000-0002-7566-1626 and Fauchier, Laurent
(2021)
The Prognosis of Baseline Mitral Regurgitation in Patients with Transcatheter Aortic Valve Implantation.
JOURNAL OF CLINICAL MEDICINE, 10 (17).
3974-.
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The Prognosis of Baseline Mitral Regurgitation in Patients with Transcatheter Aortic Valve Implantation.pdf - Published version Download (1MB) | Preview |
Abstract
Mitral regurgitation (MR) is the most common valvular lesion in transcatheter aortic valve implantation (TAVI) recipients. This study aims to assess the long-term prognostic impact of baseline MR in TAVI patients.<h4>Methods</h4>Adult patients who underwent TAVI were identified in the French National Hospital Discharge Database. All-cause and cardiovascular mortality, stroke, and rehospitalization with heart failure (HF) were compared in TAVI patients with and without baseline MR and tricuspid regurgitation (TR), respectively; the associations of MR and TR with the outcomes were assessed by Cox regression.<h4>Results</h4>Baseline MR was identified in 8240 TAVI patients. Patients with baseline MR have higher yearly incidence of all-cause mortality (HR: 1.192, 95% confidence interval CI: 1.125-1.263), cardiovascular mortality (HR: 1.313, 95%CI: 1.210-1.425), and rehospitalization for heart failure (HF) (HR: 1.411, 95%CI: 1.340-1.486) compared to those without, except for stroke rate (HR: 0.988, 95%CI: 0.868-1.124). Neither baseline MR nor TR was an independent risk predictor for all-cause mortality or cardiovascular mortality in TAVI patients. Baseline MR was independently associated with rehospitalization for HF in TAVI patients.<h4>Conclusions</h4>Baseline MR and TR were associated with increased all-cause and cardiovascular mortality post-TAVI, however, neither of them was independent predictor for all-cause or cardiovascular mortality.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | transcatheter aortic valve implantation, mitral regurgitation, tricuspid regurgitation, all-cause mortality, cardiovascular mortality |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 21 Dec 2021 16:16 |
| Last Modified: | 01 Feb 2024 02:18 |
| DOI: | 10.3390/jcm10173974 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3145819 |
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