Luo, Huanyuan, Camilleri, Dorothée, Garitaonandia, Ibon, Djumanov, Dilshat, Chen, Tao ORCID: 0000-0002-5489-6450, Lorch, Ulrike, Täubel, Jörg and Wang, Duolao
(2021)
Kinetics of anti-SARS-CoV-2 IgG antibody levels and potential influential factors in subjects with COVID-19: A 11-month follow-up study.
Diagnostic Microbiology and Infectious Disease, 101 (4).
p. 115537.
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Abstract
We aim to study kinetics of anti-SARS-CoV-2 IgG antibody levels in subjects with COVID-19 for up to 11 months and the potential influential factors. The study was a prospective longitudinal study. The analyses were based on 77 serum/plasma samples with a mean of 4 samples per participant (range 1 - 18) in 20 participants with at least one positive Polymerase Chain Reaction testing result from 19 March 2020 up to 10 February 2021. Among the subjects (median age 34.5 years, 65% male), IgG level declined with the follow-up time (per month; geometric mean ratio [GMR] 0.73; 95% CI, 0.72 - 0.74). In a small sample of subjects from the general population with COVID-19, IgG levels declined non-linearly from month 2 to 11 with individual heterogeneity in quantity and changing speed and may be associated with gender, race and the loss of smell and taste.
Item Type: | Article |
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Uncontrolled Keywords: | COVID-19, SARS-CoV-2, coronavirus, antibody, IgG, kinetics |
Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Population Health |
Depositing User: | Symplectic Admin |
Date Deposited: | 13 Jan 2022 11:47 |
Last Modified: | 18 Jan 2023 21:16 |
DOI: | 10.1016/j.diagmicrobio.2021.115537 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3146755 |
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Kinetics of anti-SARS-CoV-2 IgG antibody levels and potential influential factors in subjects with COVID-19: A 11-month follow-up study. (deposited 13 Jan 2022 11:32)
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