Rigden, Daniel J 
ORCID: 0000-0002-7565-8937 and Fernandez, Xose M
(2022)
The 2022 <i>Nucleic Acids Research</i> database issue and the online molecular biology database collection.
NUCLEIC ACIDS RESEARCH, 50 (D1).
D1-D10.
Abstract
The 2022 Nucleic Acids Research Database Issue contains 185 papers, including 87 papers reporting on new databases and 85 updates from resources previously published in the Issue. Thirteen additional manuscripts provide updates on databases most recently published elsewhere. Seven new databases focus specifically on COVID-19 and SARS-CoV-2, including SCoV2-MD, the first of the Issue's Breakthrough Articles. Major nucleic acid databases reporting updates include MODOMICS, JASPAR and miRTarBase. The AlphaFold Protein Structure Database, described in the second Breakthrough Article, is the stand-out in the protein section, where the Human Proteoform Atlas and GproteinDb are other notable new arrivals. Updates from DisProt, FuzDB and ELM comprehensively cover disordered proteins. Under the metabolism and signalling section Reactome, ConsensusPathDB, HMDB and CAZy are major returning resources. In microbial and viral genomes taxonomy and systematics are well covered by LPSN, TYGS and GTDB. Genomics resources include Ensembl, Ensembl Genomes and UCSC Genome Browser. Major returning pharmacology resource names include the IUPHAR/BPS guide and the Therapeutic Target Database. New plant databases include PlantGSAD for gene lists and qPTMplants for post-translational modifications. The entire Database Issue is freely available online on the Nucleic Acids Research website (https://academic.oup.com/nar). Our latest update to the NAR online Molecular Biology Database Collection brings the total number of entries to 1645. Following last year's major cleanup, we have updated 317 entries, listing 89 new resources and trimming 80 discontinued URLs. The current release is available at http://www.oxfordjournals.org/nar/database/c/.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Animals, Humans, Mice, Plants, Proteome, Molecular Biology, Signal Transduction, Protein Processing, Post-Translational, Genome, Viral, Databases, Factual, Databases, Nucleic Acid, Databases, Protein, Genome, Microbial, COVID-19, SARS-CoV-2 |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 07 Feb 2022 09:12 |
| Last Modified: | 27 Nov 2023 02:23 |
| DOI: | 10.1093/nar/gkab1195 |
| Open Access URL: | https://academic.oup.com/nar/article/50/D1/D1/6495... |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3148331 |
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