The Impact of Frailty and Comorbidities on Heart Failure Outcomes.

Salmon, Thomas, Essa, Hani, Tajik, Behnam ORCID: 0000-0002-8453-3909, Isanejad, Masoud ORCID: 0000-0002-3720-5152, Akpan, Asangaedem ORCID: 0000-0002-1764-8669 and Sankaranarayanan, Rajiv ORCID: 0000-0003-2355-2011 (2022) The Impact of Frailty and Comorbidities on Heart Failure Outcomes. Cardiac failure review, 8. e07-.

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Official URL: http://dx.doi.org/10.15420/cfr.2021.29

Abstract

Frailty is a multisystemic process leading to reduction of physiological reserve and a reduction in physical activity. Heart failure (HF) is recognised as a global cause of morbidity and mortality, increasing in prevalence over recent decades. Because of shared phenotypes and comorbidities, there is significant overlap and a bidirectional relationship, with frail patients being at increased risk of developing HF and vice versa. Despite this, frailty is not routinely assessed in patients with HF. Identification of these patients to direct multidisciplinary care is key, and the development of a frailty assessment tool validated in a large HF population is also an unmet need that would be of considerable benefit in directing multidisciplinary-team management. Non-pharmacological treatment should be included, as exercise and physical rehabilitation programmes offer dual benefit in frail HF patients, by treating both conditions simultaneously. The evidence for nutritional supplementation is mixed, but there is evidence that a personalised approach to nutritional support in frail HF patients can improve outcomes.

Item Type:	Article
Uncontrolled Keywords:	Frailty, comorbidity, heart failure
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Clinical Directorate Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	23 Mar 2022 10:22
Last Modified:	18 Jan 2023 21:06
DOI:	10.15420/cfr.2021.29
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3151337