Gold Nanostars Embedded in PDMS Films: A Photothermal Material for Antibacterial Applications

Toci, Gemma, Olgiati, Francesca, Pallavicini, Piersandro, Fernandez, Yuri Antonio Diaz, De Vita, Lorenzo, Dacarro, Giacomo, Grisoli, Pietro and Taglietti, Angelo (2021) Gold Nanostars Embedded in PDMS Films: A Photothermal Material for Antibacterial Applications. NANOMATERIALS, 11 (12). 3252-.

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Official URL: http://dx.doi.org/10.3390/nano11123252

Abstract

Bacteria infections and related biofilms growth on surfaces of medical devices are a serious threat to human health. Controlled hyperthermia caused by photothermal effects can be used to kill bacteria and counteract biofilms formation. Embedding of plasmonic nano-objects like gold nanostars (GNS), able to give an intense photothermal effect when irradiated in the NIR, can be a smart way to functionalize a transparent and biocompatible material like polydimethylsiloxane (PDMS). This process enables bacteria destruction on surfaces of PDMS-made medical surfaces, an action which, in principle, can also be exploited in subcutaneous devices. We prepared stable and reproducible thin PDMS films containing controllable quantities of GNS, enabling a temperature increase that can reach more than 40 degrees. The hyperthermia exerted by this hybrid material generates an effective thermal microbicidal effect, killing bacteria with a near infrared (NIR) laser source with irradiance values that are safe for skin.

Item Type:	Article
Uncontrolled Keywords:	antibacterial materials, gold nanostars, photothermal effect, hyperthermia, PDMS
Divisions:	Faculty of Science and Engineering > School of Physical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	10 May 2022 13:54
Last Modified:	18 Jan 2023 21:03
DOI:	10.3390/nano11123252
Open Access URL:	https://www.mdpi.com/2079-4991/11/12/3252
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3154551