Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch.


O'Toole, Áine ORCID: 0000-0001-8083-474X, Hill, Verity, Pybus, Oliver G, Watts, Alexander, Bogoch, Issac I ORCID: 0000-0003-1590-6748, Khan, Kamran, Messina, Jane P, COVID-19 Genomics UK (COG-UK) consortium, , Network for Genomic Surveillance in South Africa (NGS-SA), , Brazil-UK CADDE Genomic Network, et al (show 90 more authors) (2021) Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch. Wellcome open research, 6. 121-.

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Abstract

Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the international spread of lineages of concern with automated daily reports, Further, we have built a custom tracking website (cov-lineages.org/global_report.html) which hosts this daily report and will continue to include novel SARS-CoV-2 lineages of concern as they are detected.

Item Type: Article
Uncontrolled Keywords: COVID-19 Genomics UK (COG-UK) consortium, Network for Genomic Surveillance in South Africa (NGS-SA), Brazil-UK CADDE Genomic Network, Swiss Viollier Sequencing Consortium, SEARCH Alliance San Diego, National Virus Reference Laboratory, SeqCOVID-Spain, Danish Covid-19 Genome Consortium (DCGC), Communicable Diseases Genomic Network (CDGN), Dutch National SARS-CoV-2 surveillance program, Division of Emerging Infectious Diseases (KDCA)
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Depositing User: Symplectic Admin
Date Deposited: 16 May 2022 07:55
Last Modified: 18 Mar 2024 03:22
DOI: 10.12688/wellcomeopenres.16661.2
Open Access URL: https://doi.org/10.12688/wellcomeopenres.16661.2
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3154853
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