Wong, Yee Ling ORCID: 0000-0002-6109-8836, Liu, Siyin ORCID: 0000-0003-2684-4212 and Walkden, Andrew ORCID: 0000-0002-9196-6219
(2022)
Current Perspectives on Corneal Transplantation (Part 2).
Clinical ophthalmology (Auckland, N.Z.), 16.
pp. 647-659.
Abstract
Disease of the cornea is the third leading cause of blindness worldwide. Corneal graft surgery is one of the most successful forms of solid organ transplantations in humans, with ever increasing developments in surgical technique. To date, approximately 4504 corneal transplants are performed in the UK each year. While full thickness transplantation was the most commonly performed keratoplasty over the last few decades, selective lamellar transplantation of the diseased layers of the cornea has been universally adopted. This comprehensive review aims to provide an updated synthesis on different types of corneal transplantations, their treatment outcomes, and the associated complications of each procedure both in adult and pediatric populations. In addition, we also present an up-to-date summary of the emerging therapeutic approaches that have the potential to reduce the demand for donor-dependent keratoplasty.
Item Type: | Article |
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Uncontrolled Keywords: | corneal blindness, corneal transplantation, graft rejection, graft survival, keratoplasty |
Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences |
Depositing User: | Symplectic Admin |
Date Deposited: | 16 May 2022 12:33 |
Last Modified: | 18 Mar 2024 03:22 |
DOI: | 10.2147/opth.s349582 |
Open Access URL: | https://www.dovepress.com/current-perspectives-on-... |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3154899 |