Zupo, Roberta, Castellana, Fabio, De Nucci, Sara, Sila, Annamaria, Aresta, Simona, Buscemi, Carola, Randazzo, Cristiana, Buscemi, Silvio, Triggiani, Vincenzo, De Pergola, Giovanni et al (show 4 more authors)
(2022)
Role of Dietary Carotenoids in Frailty Syndrome: A Systematic Review.
BIOMEDICINES, 10 (3).
632-.
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Role of Dietary Carotenoids in Frailty Syndrome A Systematic Review.pdf - Published version Download (1MB) | Preview |
Abstract
Unbalanced diets and altered micronutrient intake are prevalent in the aging adult population. We conducted a systematic review to appraise the evidence regarding the association between single (α-carotene, β-carotene, lutein, lycopene, β-cryptoxanthin) or total carotenoids and frailty syndrome in the adult population. The literature was screened from study inception to December 2021, using six different electronic databases. After establishing inclusion criteria, two independent researchers assessed the eligibility of 180 retrieved articles. Only 11 fit the eligibility requirements, reporting five carotenoid entries. No exclusion criteria were applied to outcomes, assessment tools, i.e., frailty constructs or surrogates, recruitment setting, general health status, country, and study type (cohort or cross-sectional). Carotenoid exposure was taken as either dietary intake or serum concentrations. Cross-sectional design was more common than longitudinal design (<i>n</i> = 8). Higher dietary and plasma levels of carotenoids, taken individually or cumulatively, were found to reduce the odds of physical frailty markedly, and the evidence showed consistency in the direction of association across all selected studies. Overall, the methodological quality was rated from moderate (27%) to high (73%). Prevention of micronutrient deficiencies has some potential to counteract physical decline. Considering carotenoids as biological markers, when monitoring micronutrient status, stressing increased fruit and vegetable intake may be part of potential multilevel interventions to prevent or better manage disability.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | carotenoids, physical frailty, aging, adult population, systematic review |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 20 May 2022 15:16 |
| Last Modified: | 30 Jan 2024 20:29 |
| DOI: | 10.3390/biomedicines10030632 |
| Open Access URL: | https://www.mdpi.com/2227-9059/10/3/632 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3155244 |
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