Inhibition of Protein N- Glycosylation Blocks SARS-CoV-2 Infection


Casas-Sanchez, Aitor, Romero-Ramirez, Alessandra, Hargreaves, Eleanor, Ellis, Cameron C, Grajeda, Brian I, Estevao, Igor L, Patterson, Edward I, Hughes, Grant L, Almeida, Igor C, Zech, Tobias ORCID: 0000-0001-8394-088X et al (show 1 more authors) (2022) Inhibition of Protein N- Glycosylation Blocks SARS-CoV-2 Infection. mBio, 13 (1). e0371821-.

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Abstract

<jats:p> The coronavirus SARS-CoV-2 uses its spike surface proteins to infect human cells. Spike proteins are heavily modified with several <jats:italic>N</jats:italic> -glycans, which are predicted to modulate their function. </jats:p>

Item Type: Article
Uncontrolled Keywords: SARS-CoV-2, COVID-19, coronavirus, N-glycosylation, viral infection, antiviral agents, glycosylation
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Depositing User: Symplectic Admin
Date Deposited: 25 May 2022 09:09
Last Modified: 18 Jan 2023 21:01
DOI: 10.1128/mbio.03718-21
Open Access URL: https://doi.org/10.1128/mbio.03718-21
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3155458
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