An <i>endo</i>-Directing-Group Strategy Unlocks Enantioselective (3+1+2) Carbonylative Cycloadditions of Aminocyclopropanes

Sokolova, Olga O and Bower, John F ORCID: 0000-0002-7551-8221 (2022) An <i>endo</i>-Directing-Group Strategy Unlocks Enantioselective (3+1+2) Carbonylative Cycloadditions of Aminocyclopropanes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 61 (32). e202205007-.

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Abstract

An endo-directing group strategy enables enantioselective (3+1+2) cycloadditions that are triggered by carbonylative C-C bond activation of cyclopropanes. These processes are rare examples of cycloadditions where C-C bond oxidative addition is enantiodetermining, and the first where this is achieved within the context of a multicomponent (higher order) reaction design.

Item Type:	Article
Uncontrolled Keywords:	Cycloaddition, Cyclopropanes, Enantioselectivity, Rhodium, Synthetic Methods
Divisions:	Faculty of Science and Engineering > School of Physical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	26 May 2022 07:30
Last Modified:	15 Apr 2024 10:25
DOI:	10.1002/anie.202205007
Open Access URL:	https://doi.org/10.1002/anie.202205007%20SECTIONS
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3155513